ZHOU Xiang

Source:理学院英文网  Time:2017-12-25  Page Views:13


                                ZHOU XIANG

Associate Professor of Medicinal Chemistry

School of Science

Phone: 86-25-86185172

Email: stephanie055@163.com

Research Summary

 Dr. Zhou’s research focuses on the targeting delivery of anti-tumor drugs and diagnosis of identification of novel bioactive small molecules and the manufacture process of chemical drugs disease.

Education

2007      Ph.D., Medicinal Chemistry, China Pharmaceutical University

2002       B.S., Medicinal Chemistry, China Pharmaceutical University

Academic Experience

2012-        Associate Professor of Medicinal Chemistry

 2015-2016 Visiting Scholar, Department of Life Sciences, Pohang University of Science and Technology (POSTECH)

 2011-2012   Assistant Professor of Medicinal Chemistry

 2010-2011   Visiting Scholar, Department of Chemistry, Leiden University  

2007-2010  Assistant Professor of Medicinal Chemistry

Publications

  1. Chao Zhang, Zunfeng Liu, Ying Zheng, Yadi Geng, Chao Han, Yamin Shi, Hongbin Sun, Can Zhang, Yijun Chen, Luyong Zhang, Qinglong Guo, Lei Yang, Xiang Zhou,*and Lingyi Kong* Glycyrrhetinic Acid Functionalized Graphene Oxide for Mitochondria Targeting and Cancer Treatment In Vivo. SmallDOI: 10.1002/smll.201703306.

  2. Xiaolin Lu, Gaochao Dong , Ying Zheng , Chao Zhang , Yang Qiu , Zhisheng Wang, Tao Lu, Xiang Zhou* Synthesis and Anticancer Study of novel 4H-Chromen Derivatives. Anti-Cancer Agents in Medicinal Chemistry, 2016, 10, 1-10 .

  3. Yu Jiao, Bo-Tao Xin, Yanmin Zhang, Jianbing Wu, Xiaolin Lu, Ying Zheng, Weifang Tang, Xiang Zhou. Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl)pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents. European Journal of Medicinal Chemistry, 2015, 90, 170-183.

  4. Xiang Zhou, Fabrice Laroche, Gerda E. M. Lamers, Vincenzo Torraca, Patrick Voskamp, Tao Lu, Fuqiang Chu, Herman P. Spaink, Jan Pieter Abrahams, and Zunfeng Liu Ultra-Small Graphene Oxide Functionalized with Polyethylenimine(PEI)for Very Efficient Gene Delivery in Cell and Zebrafish Embryos. Nano Res.2012, 5, 703–709.

  5. Xiang Zhou, Xiao-Bing Wang, Tao Wang and Ling-Yi Kong, 'Rational Design, Synthesis, Biological Evaluation and 3D-QSAR Studies of Coumarin Derivatives as α1 Adreno ceptor Antagonists' Chemistry & Biodiversity2011, 8, 1052-1064.

  6. Xiang Zhou, Miao Li, Xiao-Bing Wang, Tao Wang, Ling-Yi Kong Synthesis of Benzofuran Derivatives through Rearrangement and Their Inhibitory Activity on Acetylcholinesterase. Molecules2010, 15, 8593-8601.

  7. Weimin Yang, Yadong Chen, Xiang Zhou, Yazhou Gu, Wenqi Qian, Fan Zhang, Wei Han, Tao Lu, Weifang Tang. Design, synthesis and biological evaluation of bis-aryl ureas and amides based on 2-amino-3-purinylpyridine scaffold as DFG-out B-Raf kinase inhibitors European Journal of Medicinal Chemistry, 2015, 89, 581-596.

  8. Li, Hui-Fang; Chen, Yadong; Rao, Sha-Sha; Chen, Xiu-Mei; Liu, Hai-Chun; Qin, Ji-Hong; Tang, Wei-Fang; Yue-Wang; Zhou, Xiang; Lu, Tao Recent Advances in the Research and Development of B-Raf Inhibitors Current Medicinal Chemistry, 2010, 17, 1618-1634.