YU Tao

Source:理学院英文网  Time:2017-12-26  Page Views:11

YUTAO

Lecturer of Analytical Chemistry

Email: ninayt@163.com

Research Summary

The enantioseparation of chiral drugs by capillary electrophoresis (CE).

Chirality has been and still remains a major issue in drugdevelopment and modern pharmaceutical industrybecause enantiomers of racemic drugs may exhibit differentphysiological activities as well as different even oppositepharmacokinetic and pharmacodynamic effects. Therefore, analytical methods of high efficiency and selectivity are required for both safety and industrial monitoring of theenantiomericpurity of chiral drugs. CE hasproven to be a challenging separation tool for the stereoselectiveanalysisowing to itsmajor advantages, including highseparation efficiency and resolution power, feasibility, fastanalysis, low consumptions of sample, solvent and chiralselector, as well as its high flexibility in choosing andchanging types of selectors.


Education

2012 Ph.D., Pharmaceutical Analysis, China Pharmaceutical University

2006  B.S., Traditional Chinese Medicine, China Pharmaceutical University

Academic Experience

2012-      Lecturer of Analytical Chemistry, Department of Analytical Chemistry, China PharmaceuticalUniversity

Publications

(1) Tao Yu, Yingxiang Du*, Bin Chen. Evaluation of clarithromycin lactobionate as a novel chiral selector for enantiomeric separation of basic drugs in capillary electrophoresis, Electrophoresis, 32, 1898-1905, 2011.

(2) Tao Yu, Yingxiang Du*, Jiaquan Chen, Guangfu Xu, Ke Yang, Qi Zhang, Jinjing Zhang, Shuaijing Du, Zijie Feng, Yanjie Zhang. Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis, Journal of Separation Science 38, 2900-2906, 2015.